基因合成
TBC1D15 protects alcohol-induced liver injury in female mice through PLIN5-mediated mitochondrial and lipid droplet contacting
2025.8 | Metabolism
The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer
2025.7 | Biochemical and Biophysical Research Communications
Carboxylesterase 1 regulates peroxisome proliferator-activated receptor gamma to inhibit the growth and metastasis of breast cancer cells
2025.5 | Journal of Molecular Histology
Engineered Outer Membrane Vesicles for Antigen Delivery: Exploratory Study on Adjuvant Activity and Systemic Reactogenicity
2025.5 | Vaccines
Rasal2 inhibits autophagic-exosomes secretion via regulating Rab27a in triple-negative breast cancer progression
2025.5 | Journal of Translational Medicine
An optimized integrin α6-targeted peptide capable of delivering toxins for melanoma treatment
2025.4 | Journal of Translational Medicine
Nuclear mitochondrial acetyl-CoA acetyltransferase 1 orchestrates natural killer cell-dependent antitumor immunity in colorectal cancer
2025.4 | Signal Transduction and Targeted Therapy
Enhancing genetic transformation efficiency in cucurbit crops through AtGRF5 overexpression: Mechanistic insights and applications
2025.4 | Journal of Integrative Plant Biology
Cancer-Associated Fibroblasts Foster a High-Lactate Microenvironment to Drive Perineural Invasion in Pancreatic Cancer
2025.3 | Cancer Research
circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer
2025.3 | Molecular Therapy Oncology
A synthetic heavy chain variable domain antibody library (VHL) provides highly functional antibodies with favorable developability
2025.3 | Protein Science
Identification of two new flavone 4'-O-methyltransferases and their application in de novo biosynthesis of (2S)-hesperetin in Yarrowia lipolytica
2025.3 | Synthetic and Systems Biotechnology
High-Level De Novo Production of (2S)-Naringenin in Yarrowia lipolytica Using Metabolic and Enzyme Engineering
2025.3 | ACS Agriculture Science & Technology
Deep learning prioritizes cancer mutations that alter protein nucleocytoplasmic shuttling to drive tumorigenesis
2025.3 | Nature Communications
Tailoring the polarity sensitivity of fluorescence lifetime imaging probes to reveal interplays of mitochondria dysfunction with lipid droplets formation
2025.3 | Sensors and Actuators B: Chemical
Function of lamp2 Gene Response to Vibrio vulnificus Infection and LPS Stimulation in the Half-Smooth Tongue Sole (Cynoglossus semilaevis)
2025.2 | International Journal of Molecular Sciences
Hsa-miR-526b-5p Regulates the Sensitivity of Colorectal Cancer to 5-Fluorouracil by Targeting TP53 in Organoid Models
2025.2 | Biochemical Genetics
Semi-rational engineering of glucosamine-6-phosphate deaminase for catalytic synthesis of glucosamine from D-fructose
2025.2 | Enzyme and Microbial Technology
Immobilization of Peniophora Incarnata F1 in Pva-Sa-Biochar Matrix and its Degradation Performance and Mechanism for Erythromycin Degradation
2025.2 | Journal of Environmental Management
Metabolic Engineering of Saccharomyces cerevisiae for High Bioproduction of (+)-Nootkatone
2025.2 | ACS Agriculture Science & Technology
De Novo Synthesis of Reticuline and Taxifolin Using Re-engineered Homologous Recombination in Yarrowia lipolytica
2025.2 | ACS Synthetic Biology
ZC3H13 may participate in the ferroptosis process of sepsis-induced cardiomyopathy by regulating the expression of Pnn and Rbm25
2025.1 | Gene
Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence
2025.1 | Journal of Nanobiotechnology
Comparative study of transcriptomic alterations in sepsis-induced acute liver injury: Deciphering the role of alternative splicing in mouse models
2025.1 | International Immunopharmacology
Identification of CENPM as a key gene driving adrenocortical carcinoma metastasis via physical interaction with immune checkpoint ligand FGL1
2025.1 | Clinical and Translational Medicine
Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway
2025.1 | Cell Reports
Screening of ent-copalyl diphosphate synthase and metabolic engineering to achieve de novo biosynthesis of ent-copalol in Saccharomyces cerevisiae
2024.12 | Synthetic and Systems Biotechnology
Development and Application of a Multiplex Reverse Transcription–Droplet Digital PCR Assay for Simultaneous Detection of Hepatitis A Virus and Hepatitis E Virus in Bivalve Shellfish
2024.12 | Foods
Cancer immunogenic cell death via pyroptosis with CXCR4-targeted nanotoxins in hepatocellular carcinoma
2024.11 | Front. Bioeng. Biotechnol.
Regulation of microglia inflammation and oligodendrocyte demyelination by Engeletin via the TLR4/RRP9/NF-κB pathway after spinal cord injury
2024.11 | Pharmacological Research
High efficiency production of 5-hydroxyectoine using metabolically engineered Escherichia coli
2024.9 | bioresource technology
Engineering artificial cross-species promoters with different transcriptional strengths
2024.8 | Synthetic and Systems Biotechnology
Single dose of intravenous miR199a-5p delivery targeting ischemic heart for long-term repair of myocardial infarction
2024.7 | Nature Communications
"Environmental monobutyl phthalate exposure promotes liver cancer via reprogrammed cholesterol metabolism and activation of the IRE1α-XBP1s pathway"
2024.6 | Oncogene
Screening of ent-copalyl diphosphate synthase and metabolic engineering to achieve de novo biosynthesis of ent-copalol in Saccharomyces cerevisiae
2024.6 | Synthetic and Systems Biotechnology
High-activity recombinant human carboxypeptidase B expression in Pichia pastoris through rational protein engineering and enhancing secretion from the Golgi apparatus to the plasma membrane
2024.5 | Biotechnology Journal
Overexpression of RBM15 modulated the effect of trophoblast cells by promoting the binding ability between YTHDF2 and the CD82 3′UTR to decrease the expression of CD82
2024.5 | Heliyon
Efficient Conversion of Stevioside to Rebaudioside M in Saccharomyces cerevisiae by a Engineering Hydrolase System and Prolonging the Growth Cycle
2024.4 | Journal of Agricultural and Food Chemistry
Metabolism of Inulin via Difructose Anhydride I Pathway in Microbacterium flavum
2024.4 | Journal of Agricultural and Food Chemistry
Integrated single-cell transcriptomic analyses identify a novel lineage plasticity related cancer cell type involved in prostate cancer progression
2024.4 | SSRN
LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis
2024.4 | oncogene
N6-methyladenosine-modified VGLL1 promotes ovarian cancer metastasis through high-mobility group AT-hook 1/Wnt/β-catenin signaling
2024.3 | iScience
Construction by artificial intelligence and immunovalidation of hypoallergenic mite allergen Der f 36 vaccine
2024.3 | Frontiers in Immunology
"Combining Metabolic Engineering and Lipid Droplet Assembly to Achieve Campesterol Overproduction in Saccharomyces cerevisiae"
2024.3 | Journal of Agricultural and Food Chemistry
Elucidation of the Biosynthesis of Asiaticoside and Its Reconstitution in Yeast
2024.2 | ACS Sustainable Chemistry & Engineering
Targeting the IRE1α-XBP1s axis confers selective vulnerability in hepatocellular carcinoma with activated Wnt signaling
2024.2 | Oncogene
Investigating enzyme kinetics and fluorescence sensing strategy of CRISPR/Cas12a for foodborne pathogenic bacteria
2024.2 | Analytica Chimica Acta
Nup210 promotes colorectal cancer progression by regulating nuclear plasma transport
2024.1 | Laboratory Investigation
Innovative application of a novel and thermostable inulin fructotransferase from Arthrobacter sp. ISL-85 to fructan inulin in burdock root to improve nutrition
2024.1 | Food Chemistry
Cryptotanshinone Inhibits Bladder Cancer Cell Malignant Progression in a Lipopolysaccharide-Induced Inflammatory Microenvironment through NLRP3 Inhibition
2024.1 | Mediators of Inflammation
Hydrogen gas inhibits neuroinflammation after traumatic brain injury by promoting microglia M2 polarization via AMPK-dependent mediation of HDAC5
2024.1 | Research Square
A dual-function selection system enables positive selection of multigene CRISPR mutants and negative selection of Cas9-free progeny in Arabidopsis
2024.1 | aBIOTECH
Synergetic Engineering of Multiple Pathways for De Novo (2S)-Naringenin Biosynthesis in Saccharomyces cerevisiae
2023.12 | ACS Sustainable Chemistry & Engineering
Artificial intelligence-driven design of the assembled major cat allergen Fel d 1 to improve its spatial folding and IgE-reactivity
2023.12 | International Immunopharmacology
The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation
2023.12 | Cellular & Molecular Immunology
Enhancing Glycosylation of Flavonoids by Engineering the Uridine Diphosphate Glucose Supply in Escherichia coli
2023.11 | Journal of Agricultural and Food Chemistry
Long non-coding RNA APDC plays important regulatory roles in metabolism of bone and adipose tissues
2023.11 | RNA Biology
"Metabolic engineering combined with enzyme engineering for overproduction of ectoine in Escherichia coli"
2023.10 | Bioresource Technology
METTL14 inhibits malignant progression of oral squamous cell carcinoma by targeting the autophagy-related gene RB1CC1 in an m6A-IGF2BP2-dependent manner
2023.9 | Clinical Science
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy
2023.9 | JACC Basic Transl Sci
PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function
2023.9 | Redox Biology
Colloidal gold-based immunochromatographic biosensor for quantitative detection of S100B in serum samples
2023.8 | Nanoscale Horizons
Core–Shell Droplet-Based Microfluidic Screening System for Filamentous Fungi
2023.8 | ACS Sensors
Immunosensitivity mediated by downregulated AKT1-SKP2 induces anti-PD-1-associated thyroid immune injury
2023.6 | International Immunopharmacology
STAT4‑Mediated Klotho Up‑Regulation Contributes to the Brain Ischemic Tolerance by Cerebral Ischemic Preconditioning via Inhibiting Neuronal Pyroptosis
2023.1 | Molecular Neurobiology
"CPT1A promotes anoikis resistance in esophageal squamous cell carcinoma via redox homeostasis"
2022.12 | Redox Biology
"Circular RNA hsa_circ_0011324 is involved in endometrial cancer progression and the evolution of its mechanism"
2022.3 | Bioengineered
Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis
2022.2 | Signal Transduction and Targeted Therapy
Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming
2022.1 | Theranostics
siRNA合成
Acetyl zingerone inhibits chondrocyte pyroptosis and alleviates osteoarthritis progression by promoting mitophagy through the PINK1/parkin signaling pathway
2025.8 | International Immunopharmacology
Hydrogen sulfide preserves the function of senescent endothelium through SIRT2 mediated inflammatory inhibition
2025.6 | Journal of Molecular and Cellular Cardiology
Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p
2025.6 | International Journal of Biological Macromolecules
"GalNAc-siRNA conjugates mediate the silencing of the parasite-derived lncRNA: A novel therapeutic approach for liver fluke-induced liver fibrosis"
2025.6 | International Journal of Biological Macromolecules
"ProgrammedCellDeathProtein10(PDCD10)Regulates VesicleTraffickingandContributestotheProgressionof ClearCellRenalCellCarcinoma"
2025.5 | Journal of Extracellular Vesicles
Homeobox C6 plays an oncogenic role in bladder cancer
2025.5 | World J Clin Oncol.
Total ginsenosides and ginsenoside Rb2 delay hepatocyte senescence by regulating NAD+ metabolism and promoting IDO2/QPRT expression
2025.5 | Journal of Ginseng Research
Discovery of Yersinia LcrV as a novel biased agonist of formyl peptide receptor 1 to bi-directionally modulate intracellular kinases in triple-negative breast cancer
2025.5 | Acta Pharmaceutica Sinica
The comprehensive transcriptomic atlas of porcine immune tissues and the early peripheral blood mononuclear cell (PBMC) immune dynamics reveal core immune genes
2025.5 | Journal of Animal Science and Biotechnology
Cancer-Associated Fibroblasts Foster a High-Lactate Microenvironment to Drive Perineural Invasion in Pancreatic Cancer
2025.3 | Cancer Research
circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer
2025.3 | Molecular Therapy Oncology
The Pb tolerance initiated by LdZIP8 in Lymantria dispar larvae: An effective defense against heavy metal stress
2025.3 | Journal of Hazardous Materials
Function of lamp2 Gene Response to Vibrio vulnificus Infection and LPS Stimulation in the Half-Smooth Tongue Sole (Cynoglossus semilaevis)
2025.2 | International Journal of Molecular Sciences
Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study
2025.2 | british journal of cancer
Integrative bioinformatics and experimental analyses identify U2SURP as a novel lactylation-related prognostic signature in esophageal carcinoma
2025.2 | Immunologic Research
Exosomes of human adipose stem cells mitigate irradiation injury to salivary glands by inhibiting epithelial-mesenchymal transition through miR-199a-3p targeting Twist1 and regulating TGFβ1/Smad3 pathway
2025.1 | Theranostics
Cold atmospheric plasma potentiates ferroptosis via EGFR(Y1068)-mediated dual axes on GPX4 among triple negative breast cancer cells
2025.1 | International Journal of Biological Sciences
IL-8 promotes pyroptosis through ERK pathway and mediates glucocorticoid resistance in chronic rhinosinusitis with nasal polyps
2025.1 | Inflammation Research
Circular RNA circPHLPP2 promotes tumor growth and anti-PD-1 resistance through binding ILF3 to regulate IL36γ transcription in colorectal cancer
2024.12 | Molecular Cancer
Microplastics accumulated in breast cancer patients lead to mitophagy via ANXA2-mediated endocytosis and IL-17 signaling pathway
2024.11 | Environmental Pollution
Prebiotic stachyose inhibits PRDX5 activity and castration-resistant prostate cancer development
2024.1 | International Journal of Biological Macromolecules
Fluoride exposure-induced gut microbiota alteration mediates colonic ferroptosis through N6-methyladenosine (m6A) mediated silencing of SLC7A11
2024.9 | Ecotoxicology and Environmental Safety
Lysosomal dysfunction-derived autophagy impairment of gingival epithelial cells in diabetes-associated periodontitis with altered protein acetylation
2024.9 | Cellular Signalling
Construction of a prognostic model for ovarian cancer based on a comprehensive bioinformatics analysis of cuproptosis-associated long non-coding RNA signatures
2024.8 | Heliyon
Arsenic trioxide suppresses lung adenocarcinoma stem cell stemness by inhibiting m6A modification to promote ferroptosis
2024.2 | Am J Cancer Res.
The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis
2024.2 | Cell Discovery
Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts
2024.1 | Pharmaceuticals
Prognosis and immunotherapy response prediction based on M2 macrophage-related genes in colon cancer
2024.1 | Journal of Cancer Research and Clinical Oncology
"Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer"
2023.12 | Advanced Science
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy
2023.9 | JACC Basic Transl Sci
PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function
2023.9 | Redox Biology
"Assessment of prognostic role of a novel 7-lncRNA signature in HCC patients"
2023.7 | Heliyou
SERPINB5 is a prognostic biomarker and promotes proliferation, metastasis and epithelial-mesenchymal transition (EMT) in lung adenocarcinoma
2023.7 | Thoracic Cancer
"lncRNA CYTOR Facilitates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating SOX11 via Sponging miR-6512-3p"
2023.3 | Stem Cells International
"LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway"
2023.1 | EUROPEAN JOURNAL OF HISTOCHEMISTRY
Transcriptomic and Functional Approaches Unveil the Role of tmRNA in Zinc Acetate Mediated Levofloxacin Sensitivity in Helicobacter pylori
2022.11 | Microbiology Spectrum
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells
2022.7 | Cell Death & Disease
shRNA合成
The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer
2025.7 | Biochemical and Biophysical Research Communications
Tea Polyphenols Mitigate Radiation-Induced Ferroptosis and Intestinal Injury by Targeting the Nrf2/HO-1/GPX4 Signaling Pathway
2025.5 | Antioxidants
The Potential Biological Roles and Clinical Significance of Anaphase-Promoting Complex Subunit 1 in Colorectal Cancer
2025.4 | Cancer control
Cancer-associated fibroblasts promote oral squamous cell carcinoma progression by targeting ATP7A via exosome-mediated paracrine miR-148b-3p
2025.4 | Cellular Signalling
UBC9: a novel therapeutic target in papillary thyroid carcinoma
2025.3 | Journal of Endocrinological Investigation
CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis
2024.5 | Technology in Cancer Research & Treatment
N6-methyladenosine-modified VGLL1 promotes ovarian cancer metastasis through high-mobility group AT-hook 1/Wnt/β-catenin signaling
2024.3 | iScience
ALKBH5 Protects Against Hepatic Ischemia–Reperfusion Injury by Regulating YTHDF1-Mediated YAP Expression
2024.1 | International Journal of Molecular Sciences
METTL14 inhibits malignant progression of oral squamous cell carcinoma by targeting the autophagy-related gene RB1CC1 in an m6A-IGF2BP2-dependent manner
2023.9 | Clinical Science
miRNA合成
Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p
2025.6 | International Journal of Biological Macromolecules
circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer
2025.3 | Molecular Therapy Oncology
Hsa-miR-526b-5p Regulates the Sensitivity of Colorectal Cancer to 5-Fluorouracil by Targeting TP53 in Organoid Models
2025.2 | Biochemical Genetics
Brain‐Derived Exosomal miR‐9‐5p Induces Ferroptosis in Traumatic Brain Injury‐Induced Acute Lung Injury by Targeting Scd1
2024.12 | CNS Neurosci Ther
Regulation of mRNA and miRNA in the response to Salmonella enterica serovar Enteritidis infection in chicken cecum
2022.12 | BMC Veterinary Research
"Downregulation of hsa_circRNA_0001400 Helps to Promote Cell Apoptosis Through Disruption of the circRNA_0001400–miR-326 Sponge in Cervical Cancer Cells"
2021.12 | Frontiers in Genetics
RNA合成
Acetyl zingerone inhibits chondrocyte pyroptosis and alleviates osteoarthritis progression by promoting mitophagy through the PINK1/parkin signaling pathway
2025.8 | International Immunopharmacology
Hydrogen sulfide preserves the function of senescent endothelium through SIRT2 mediated inflammatory inhibition
2025.6 | Journal of Molecular and Cellular Cardiology
Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p
2025.6 | International Journal of Biological Macromolecules
"GalNAc-siRNA conjugates mediate the silencing of the parasite-derived lncRNA: A novel therapeutic approach for liver fluke-induced liver fibrosis"
2025.6 | International Journal of Biological Macromolecules
"ProgrammedCellDeathProtein10(PDCD10)Regulates VesicleTraffickingandContributestotheProgressionof ClearCellRenalCellCarcinoma"
2025.5 | Journal of Extracellular Vesicles
Homeobox C6 plays an oncogenic role in bladder cancer
2025.5 | World J Clin Oncol.
Total ginsenosides and ginsenoside Rb2 delay hepatocyte senescence by regulating NAD+ metabolism and promoting IDO2/QPRT expression
2025.5 | Journal of Ginseng Research
Discovery of Yersinia LcrV as a novel biased agonist of formyl peptide receptor 1 to bi-directionally modulate intracellular kinases in triple-negative breast cancer
2025.5 | Acta Pharmaceutica Sinica
The comprehensive transcriptomic atlas of porcine immune tissues and the early peripheral blood mononuclear cell (PBMC) immune dynamics reveal core immune genes
2025.5 | Journal of Animal Science and Biotechnology
Cancer-Associated Fibroblasts Foster a High-Lactate Microenvironment to Drive Perineural Invasion in Pancreatic Cancer
2025.3 | Cancer Research
circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer
2025.3 | Molecular Therapy Oncology
The Pb tolerance initiated by LdZIP8 in Lymantria dispar larvae: An effective defense against heavy metal stress
2025.3 | Journal of Hazardous Materials
Function of lamp2 Gene Response to Vibrio vulnificus Infection and LPS Stimulation in the Half-Smooth Tongue Sole (Cynoglossus semilaevis)
2025.2 | International Journal of Molecular Sciences
Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study
2025.2 | british journal of cancer
Integrative bioinformatics and experimental analyses identify U2SURP as a novel lactylation-related prognostic signature in esophageal carcinoma
2025.2 | Immunologic Research
Exosomes of human adipose stem cells mitigate irradiation injury to salivary glands by inhibiting epithelial-mesenchymal transition through miR-199a-3p targeting Twist1 and regulating TGFβ1/Smad3 pathway
2025.1 | Theranostics
Cold atmospheric plasma potentiates ferroptosis via EGFR(Y1068)-mediated dual axes on GPX4 among triple negative breast cancer cells
2025.1 | International Journal of Biological Sciences
IL-8 promotes pyroptosis through ERK pathway and mediates glucocorticoid resistance in chronic rhinosinusitis with nasal polyps
2025.1 | Inflammation Research
Circular RNA circPHLPP2 promotes tumor growth and anti-PD-1 resistance through binding ILF3 to regulate IL36γ transcription in colorectal cancer
2024.12 | Molecular Cancer
Microplastics accumulated in breast cancer patients lead to mitophagy via ANXA2-mediated endocytosis and IL-17 signaling pathway
2024.11 | Environmental Pollution
Prebiotic stachyose inhibits PRDX5 activity and castration-resistant prostate cancer development
2024.1 | International Journal of Biological Macromolecules
Fluoride exposure-induced gut microbiota alteration mediates colonic ferroptosis through N6-methyladenosine (m6A) mediated silencing of SLC7A11
2024.9 | Ecotoxicology and Environmental Safety
Lysosomal dysfunction-derived autophagy impairment of gingival epithelial cells in diabetes-associated periodontitis with altered protein acetylation
2024.9 | Cellular Signalling
Construction of a prognostic model for ovarian cancer based on a comprehensive bioinformatics analysis of cuproptosis-associated long non-coding RNA signatures
2024.8 | Heliyon
Arsenic trioxide suppresses lung adenocarcinoma stem cell stemness by inhibiting m6A modification to promote ferroptosis
2024.2 | Am J Cancer Res.
The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis
2024.2 | Cell Discovery
Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts
2024.1 | Pharmaceuticals
Prognosis and immunotherapy response prediction based on M2 macrophage-related genes in colon cancer
2024.1 | Journal of Cancer Research and Clinical Oncology
The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer
2025.7 | Biochemical and Biophysical Research Communications
"Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer"
2023.12 | Advanced Science
Tea Polyphenols Mitigate Radiation-Induced Ferroptosis and Intestinal Injury by Targeting the Nrf2/HO-1/GPX4 Signaling Pathway
2025.5 | Antioxidants
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy
2023.9 | JACC Basic Transl Sci
The Potential Biological Roles and Clinical Significance of Anaphase-Promoting Complex Subunit 1 in Colorectal Cancer
2025.4 | Cancer control
PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function
2023.9 | Redox Biology
Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p
2025.6 | International Journal of Biological Macromolecules
Cancer-associated fibroblasts promote oral squamous cell carcinoma progression by targeting ATP7A via exosome-mediated paracrine miR-148b-3p
2025.4 | Cellular Signalling
"Assessment of prognostic role of a novel 7-lncRNA signature in HCC patients"
2023.7 | Heliyou
UBC9: a novel therapeutic target in papillary thyroid carcinoma
2025.3 | Journal of Endocrinological Investigation
circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer
2025.3 | Molecular Therapy Oncology
SERPINB5 is a prognostic biomarker and promotes proliferation, metastasis and epithelial-mesenchymal transition (EMT) in lung adenocarcinoma
2023.7 | Thoracic Cancer
Hsa-miR-526b-5p Regulates the Sensitivity of Colorectal Cancer to 5-Fluorouracil by Targeting TP53 in Organoid Models
2025.2 | Biochemical Genetics
CRISPR-Cas12a2-based rapid and sensitive detection system for target nucleic acid
2025.2 | International Journal of Biological Macromolecules
CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis
2024.5 | Technology in Cancer Research & Treatment
"lncRNA CYTOR Facilitates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating SOX11 via Sponging miR-6512-3p"
2023.3 | Stem Cells International
N6-methyladenosine-modified VGLL1 promotes ovarian cancer metastasis through high-mobility group AT-hook 1/Wnt/β-catenin signaling
2024.3 | iScience
Hairpin-locker mediated CRISPR/Cas tandem system for ultrasensitive detection of DNA without pre-amplification
2024.3 | Microchemical Journal
Brain‐Derived Exosomal miR‐9‐5p Induces Ferroptosis in Traumatic Brain Injury‐Induced Acute Lung Injury by Targeting Scd1
2024.12 | CNS Neurosci Ther
"LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway"
2023.1 | EUROPEAN JOURNAL OF HISTOCHEMISTRY
ALKBH5 Protects Against Hepatic Ischemia–Reperfusion Injury by Regulating YTHDF1-Mediated YAP Expression
2024.1 | International Journal of Molecular Sciences
"Icariin promotes osteogenic differentiation through the mmu_circ_0000349/mmu-miR-138-5p/Jumonji domain-containing protein-3 axis"
2023.11 | Heliyou
Regulation of mRNA and miRNA in the response to Salmonella enterica serovar Enteritidis infection in chicken cecum
2022.12 | BMC Veterinary Research
Transcriptomic and Functional Approaches Unveil the Role of tmRNA in Zinc Acetate Mediated Levofloxacin Sensitivity in Helicobacter pylori
2022.11 | Microbiology Spectrum
METTL14 inhibits malignant progression of oral squamous cell carcinoma by targeting the autophagy-related gene RB1CC1 in an m6A-IGF2BP2-dependent manner
2023.9 | Clinical Science
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells
2022.7 | Cell Death & Disease
Autophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA
2022.1 | Nature Communications
"Downregulation of hsa_circRNA_0001400 Helps to Promote Cell Apoptosis Through Disruption of the circRNA_0001400–miR-326 Sponge in Cervical Cancer Cells"
2021.12 | Frontiers in Genetics
引物探针
Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease
2025.5 | Theranostics
Carboxylesterase 1 regulates peroxisome proliferator-activated receptor gamma to inhibit the growth and metastasis of breast cancer cells
2025.5 | Journal of Molecular Histology
Ziziphi Spinosae semen extract ameliorates insomnia by regulating hypothalamic GABA/Glu balance and gut microbiota Lactobacillus johnsonii
2025.5 | Journal of Functional Foods
Identification of genetic indicators linked to immunological infiltration in idiopathic pulmonary fibrosis
2025.5 | Medicine
Regulation of Dendritic Cell Function by RFX5 through Interaction with HDAC2 and Its Mechanism in Pediatric Asthma
2025.4 | Biocell
Engineering an Extremely Monoterpene-Tolerant Serratia marcescens for High-Yield Geraniol Production via a Rationally Modified Insect Phosphatase
2025.4 | ACS Sustainable Chemistry & Engineering
Production of geraniol by a solvent-tolerant Serratia marcescens without the formation of geraniol derivatives
2025.4 | Biocatalysis and Agricultural Biotechnology
Hybrid Methylotrophic Pathway in Serratia marcescens for Sustainable Terpenoid Biosynthesis
2025.4 | ACS Synthetic Biology
Multi-omics integration reveals the regulatory mechanisms of APC and CREB5 genes in lipid biosynthesis and fatty acid composition in pigs
2025.3 | Food Chemistry
Semi-rational engineering of glucosamine-6-phosphate deaminase for catalytic synthesis of glucosamine from D-fructose
2025.2 | Enzyme and Microbial Technology
"Construction of a CRISPR‐Cas9‐Based Genetic Editing Tool for Serratia marcescens Using a Stationary Phase Promoter and Its Application in Putrescine Production"
2025.2 | Biotechnology and Bioengineering
Rapid detection assays for Bacillus anthracis, Yersinia pestis, and Brucella spp. via triplex-recombinase polymerase amplification
2025.1 | Molecular Biology Reports
Development of a vitamin B5 hyperproducer in Escherichia coli by multiple metabolic engineering
2024.7 | Metabolic Engineering
Ferulic Acid Relieves the Oxidative Stress Induced by Oxidized Fish Oil in Oriental River Prawn (Macrobrachium Nipponense) with the Emphasis on Lipid Metabolism and Gut Microbiota
2024.4 | SSRN
Characterization and Application of a Stationary Phase Promoter Library from Serratia marcescens
2024.3 | ACS Sustainable Chemistry & Engineering
Hairpin-locker mediated CRISPR/Cas tandem system for ultrasensitive detection of DNA without pre-amplification
2024.3 | Microchemical Journal
Synergetic Engineering of Multiple Pathways for De Novo (2S)-Naringenin Biosynthesis in Saccharomyces cerevisiae
2023.12 | ACS Sustainable Chemistry & Engineering
Sanger测序
Itaconic acid production from corn stover hydrolysates for a newly isolated Aspergillus terreus through adaptive evolution
2025.4 | Bioprocess and Biosystems Engineering
De novo production of LNnT by metabolic engineering of Saccharomyces cerevisiae as cell factory
2024.11 | FOOD SCIENCE AND HUMAN WELLNESS
Taurine-mediated gene transcription and cell membrane permeability reinforced co-production of bioethanol and Monascus azaphilone pigments for a newly isolated Monascus purpureus
2024.5 | Biotechnology for Biofuels and Bioproducts
Isolation and genomic characterization of chicken infectious anemia virus in Jiangsu province of China during 2020–2022
2024.3 | Frontiers in Veterinary Science
Development of Terminator–Promoter Bifunctional Elements for Application in Saccharomyces cerevisiae Pathway Engineering
2023.6 | International Journal of Molecular Sciences
"Characterisation of Aldo-keto Reductases From Lactobacillus reuteri DSM20016"
2022.11 | Process Biochemistry
"Heterologous expression and characterization of a borneol dehydrogenase from Arabidopsis lyrate and its application for the enzymatic resolution of rac-camphor"
2022.9 | Molecular Catalysis
"Glycosylation Modification Enhances (2S)‑Naringenin Production in Saccharomyces cerevisiae"
2022.6 | ACS Synthetic Biology
"Enhancing Squalene Production in Saccharomyces cerevisiae by Metabolic Engineering and Random Mutagenesis"
2022.1 | Frontiers in Chemical Engineering
Expression and characterization of a raw-starch glucoamylase from Aspergillus fumigatus
2021.1 | Process Biochemistry
转染试剂
Hydrogen sulfide preserves the function of senescent endothelium through SIRT2 mediated inflammatory inhibition
2025.6 | Journal of Molecular and Cellular Cardiology
Berberine attenuates obesity-induced skeletal muscle atrophy via regulation of FUNDC1 in skeletal muscle of mice
2025.2 | Scientific Reports
Single-cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia–reperfusion injury
2024.11 | FASEB Journal
PAI-1 Derived from Alveolar Type 2 Cells Drives Aging-Associated Pulmonary Fibrosis
2024.9 | Engineering
A Novel Four-CpG Prognostic Risk Score Model Predicts Survival and Guides Therapy in Patients with Head and Neck Squamous Cell Carcinoma
2024.9 | Preprint