Photocatalytic NAD(P)H regeneration by alkali-doped g-C3N4 and extending visible light to near-infrared light

Copper orchestrates triple-negative breast cancer progression via the STEAP3-dependent CDK16-JAK1 activation

Integrated one-pot RPA-CRISPR/Cas13a platform enables ultrasensitive and field-deployable JAK2 V617F detection for myeloproliferative neoplasm diagnosis

Identification of O-GalNAc-modified proteins interacting with GALNT3 using proximity labeling method

Apoptotic extracellular vesicles from peripancreatic adipose-derived mesenchymal stem cells ameliorate severe acute pancreatitis through the transcription factor EB-mediated autophagy–lysosomal pathway: an experimental study

Elevated NDRG1 Expression Drives Oxaliplatin Chemoresistance in Bladder Cancer Cells by Promoting Homologous Recombination Repair and Inhibiting G2/M Arrest

Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents

A Soluble Receptor for Advanced Glycation End-Products Attenuates Myocardial Ischemia/Reperfusion Injury via Enhancing Glucose Metabolism

Efficient synthesis of chiral heterocyclic alcohols by designed carbonyl reductases with coenzyme regeneration system

A modular and universal platform for neutralizing-antibody profiling by quantifying antigen-receptor interactions via qPCR

SERPINH1 promotes malignant progression of laryngeal squamous cell carcinoma via COL7A1-mediated Wnt/β-catenin signaling

Knockdown of Nr4a3 mitigates acute pancreatitis-induced injury by modulating Btg2 to reduce oxidative stress, mitochondrial damage, and apoptosis

SOX11-mediated CBLN2 Upregulation Contributes to Neuropathic Pain through NF-κB-Driven Neuroinflammation in Dorsal Root Ganglia of Mice

A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy

Engineering a robust and versatile terpenoid production platform in Serratia marcescens HBQA7

CREB–KIF1A–CGRP-positive feedback loop drives central sensitization in chronic migraine

TSC22D1 promotes liver sinusoidal endothelial cell dysfunction and induces macrophage M1 polarization in non-alcoholic fatty liver disease

A novel dominant negative variant of ALPL induces hypophosphatasia

Multi-strategy metabolic reprogramming of Serratia marcescens HBQA7 for high-efficiency spermidine biosynthesis via the carboxyaminopropylagmatine pathway

TBC1D15 protects alcohol-induced liver injury in female mice through PLIN5-mediated mitochondrial and lipid droplet contacting

Comprehensive Mining of Lung Adenocarcinoma Biomarkers and Rational Design of Functional Probes for Enhanced Diagnostic and Therapeutic Applications

LNP-enclosed NamiRNA inhibits pancreatic cancer proliferation and migration via dual pathways

circFTO binding with IGF2BP2 regulates trophoblast cells proliferation, migration, and invasion while mediating m6A modification of CCAR1 mRNA in spontaneous abortion

The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer

Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p

Carboxylesterase 1 regulates peroxisome proliferator-activated receptor gamma to inhibit the growth and metastasis of breast cancer cells

Engineered Outer Membrane Vesicles for Antigen Delivery: Exploratory Study on Adjuvant Activity and Systemic Reactogenicity

Rasal2 inhibits autophagic-exosomes secretion via regulating Rab27a in triple-negative breast cancer progression

An optimized integrin α6-targeted peptide capable of delivering toxins for melanoma treatment

Nuclear mitochondrial acetyl-CoA acetyltransferase 1 orchestrates natural killer cell-dependent antitumor immunity in colorectal cancer

Enhancing genetic transformation efficiency in cucurbit crops through AtGRF5 overexpression: Mechanistic insights and applications

Cancer-Associated Fibroblasts Foster a High-Lactate Microenvironment to Drive Perineural Invasion in Pancreatic Cancer

circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer

A synthetic heavy chain variable domain antibody library (VHL) provides highly functional antibodies with favorable developability

Identification of two new flavone 4'-O-methyltransferases and their application in de novo biosynthesis of (2S)-hesperetin in Yarrowia lipolytica

High-Level De Novo Production of (2S)-Naringenin in Yarrowia lipolytica Using Metabolic and Enzyme Engineering

Deep learning prioritizes cancer mutations that alter protein nucleocytoplasmic shuttling to drive tumorigenesis

Tailoring the polarity sensitivity of fluorescence lifetime imaging probes to reveal interplays of mitochondria dysfunction with lipid droplets formation

Function of lamp2 Gene Response to Vibrio vulnificus Infection and LPS Stimulation in the Half-Smooth Tongue Sole (Cynoglossus semilaevis)

Hsa-miR-526b-5p Regulates the Sensitivity of Colorectal Cancer to 5-Fluorouracil by Targeting TP53 in Organoid Models

Semi-rational engineering of glucosamine-6-phosphate deaminase for catalytic synthesis of glucosamine from D-fructose

Immobilization of Peniophora Incarnata F1 in Pva-Sa-Biochar Matrix and its Degradation Performance and Mechanism for Erythromycin Degradation

Metabolic Engineering of Saccharomyces cerevisiae for High Bioproduction of (+)-Nootkatone

De Novo Synthesis of Reticuline and Taxifolin Using Re-engineered Homologous Recombination in Yarrowia lipolytica

ZC3H13 may participate in the ferroptosis process of sepsis-induced cardiomyopathy by regulating the expression of Pnn and Rbm25

Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence

Comparative study of transcriptomic alterations in sepsis-induced acute liver injury: Deciphering the role of alternative splicing in mouse models

Identification of CENPM as a key gene driving adrenocortical carcinoma metastasis via physical interaction with immune checkpoint ligand FGL1

Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway

Screening of ent-copalyl diphosphate synthase and metabolic engineering to achieve de novo biosynthesis of ent-copalol in Saccharomyces cerevisiae

Development and Application of a Multiplex Reverse Transcription–Droplet Digital PCR Assay for Simultaneous Detection of Hepatitis A Virus and Hepatitis E Virus in Bivalve Shellfish

Cancer immunogenic cell death via pyroptosis with CXCR4-targeted nanotoxins in hepatocellular carcinoma

Regulation of microglia inflammation and oligodendrocyte demyelination by Engeletin via the TLR4/RRP9/NF-κB pathway after spinal cord injury

High efficiency production of 5-hydroxyectoine using metabolically engineered Escherichia coli

Engineering artificial cross-species promoters with different transcriptional strengths

Single dose of intravenous miR199a-5p delivery targeting ischemic heart for long-term repair of myocardial infarction

"Environmental monobutyl phthalate exposure promotes liver cancer via reprogrammed cholesterol metabolism and activation of the IRE1α-XBP1s pathway"

Screening of ent-copalyl diphosphate synthase and metabolic engineering to achieve de novo biosynthesis of ent-copalol in Saccharomyces cerevisiae

High-activity recombinant human carboxypeptidase B expression in Pichia pastoris through rational protein engineering and enhancing secretion from the Golgi apparatus to the plasma membrane

Overexpression of RBM15 modulated the effect of trophoblast cells by promoting the binding ability between YTHDF2 and the CD82 3′UTR to decrease the expression of CD82

Efficient Conversion of Stevioside to Rebaudioside M in Saccharomyces cerevisiae by a Engineering Hydrolase System and Prolonging the Growth Cycle

Metabolism of Inulin via Difructose Anhydride I Pathway in Microbacterium flavum

Integrated single-cell transcriptomic analyses identify a novel lineage plasticity related cancer cell type involved in prostate cancer progression

LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis

N6-methyladenosine-modified VGLL1 promotes ovarian cancer metastasis through high-mobility group AT-hook 1/Wnt/β-catenin signaling

Construction by artificial intelligence and immunovalidation of hypoallergenic mite allergen Der f 36 vaccine

"Combining Metabolic Engineering and Lipid Droplet Assembly to Achieve Campesterol Overproduction in Saccharomyces cerevisiae"

Elucidation of the Biosynthesis of Asiaticoside and Its Reconstitution in Yeast

Targeting the IRE1α-XBP1s axis confers selective vulnerability in hepatocellular carcinoma with activated Wnt signaling

Investigating enzyme kinetics and fluorescence sensing strategy of CRISPR/Cas12a for foodborne pathogenic bacteria

Nup210 promotes colorectal cancer progression by regulating nuclear plasma transport

Innovative application of a novel and thermostable inulin fructotransferase from Arthrobacter sp. ISL-85 to fructan inulin in burdock root to improve nutrition

Cryptotanshinone Inhibits Bladder Cancer Cell Malignant Progression in a Lipopolysaccharide-Induced Inflammatory Microenvironment through NLRP3 Inhibition

Hydrogen gas inhibits neuroinflammation after traumatic brain injury by promoting microglia M2 polarization via AMPK-dependent mediation of HDAC5

A dual-function selection system enables positive selection of multigene CRISPR mutants and negative selection of Cas9-free progeny in Arabidopsis

Synergetic Engineering of Multiple Pathways for De Novo (2S)-Naringenin Biosynthesis in Saccharomyces cerevisiae

Artificial intelligence-driven design of the assembled major cat allergen Fel d 1 to improve its spatial folding and IgE-reactivity

The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation

Enhancing Glycosylation of Flavonoids by Engineering the Uridine Diphosphate Glucose Supply in Escherichia coli

Long non-coding RNA APDC plays important regulatory roles in metabolism of bone and adipose tissues

"Metabolic engineering combined with enzyme engineering for overproduction of ectoine in Escherichia coli"

METTL14 inhibits malignant progression of oral squamous cell carcinoma by targeting the autophagy-related gene RB1CC1 in an m6A-IGF2BP2-dependent manner

Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy

PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function

Colloidal gold-based immunochromatographic biosensor for quantitative detection of S100B in serum samples

Core–Shell Droplet-Based Microfluidic Screening System for Filamentous Fungi

Immunosensitivity mediated by downregulated AKT1-SKP2 induces anti-PD-1-associated thyroid immune injury

STAT4‑Mediated Klotho Up‑Regulation Contributes to the Brain Ischemic Tolerance by Cerebral Ischemic Preconditioning via Inhibiting Neuronal Pyroptosis

"CPT1A promotes anoikis resistance in esophageal squamous cell carcinoma via redox homeostasis"

"Circular RNA hsa_circ_0011324 is involved in endometrial cancer progression and the evolution of its mechanism"

Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis

Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming

Chaihu Guizhi Ganjiang decoction attenuates chronic pancreatitis by suppressing acinar cell ferroptosis via regulating p53/SLC7A11/GPX4 pathway

Apoptotic extracellular vesicles from peripancreatic adipose-derived mesenchymal stem cells ameliorate severe acute pancreatitis through the transcription factor EB-mediated autophagy–lysosomal pathway: an experimental study

Remimazolam attenuates traumatic brain injury-induced acute lung injury by suppressing pulmonary epithelial pyroptosis

The m6A reader protein YTHDF2 facilitates HTLV-1 infectious and mitotic propagation by stabilizing Tax RNA

Tenvermectin B, a novel macrocyclic lactone antibiotic, suppresses glioblastoma progression by targeting RhoJ

ZBTB16 promotes the transcription of glycolytic enzyme PFKFB2 to participate in fibrogenesis in septic lung injury

"Obinutuzumab induces lysosomal destabilization via sphingomyelin-dependent inhibition of TRPML2"

"USP25 attenuates the immunosuppressive tumor microenvironment via the deubiquitination of TAB2 in head and neck squamous cell carcinoma"

Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis

Cellular and molecular mechanisms of seahorse male pregnancy

PRRX1 Orchestrates Pericyte–Myofibroblast Transition in Pathological Retinal Fibrosis

A Soluble Receptor for Advanced Glycation End-Products Attenuates Myocardial Ischemia/Reperfusion Injury via Enhancing Glucose Metabolism

CD81 inhibits the proliferation of acute megakaryoblastic leukemia cells

SOX11-mediated CBLN2 Upregulation Contributes to Neuropathic Pain through NF-κB-Driven Neuroinflammation in Dorsal Root Ganglia of Mice

MIOX Aggravated DEHP-Induced Ferroptosis in Chicken Hepatocytes by Targeting STAT3 Phosphorylation

CREB–KIF1A–CGRP-positive feedback loop drives central sensitization in chronic migraine

Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells

Critical role of LdZIP7 in enhancing cadmium tolerance of Lymantria dispar larvae: Functional identification at both the individual and cellular levels

Acetyl zingerone inhibits chondrocyte pyroptosis and alleviates osteoarthritis progression by promoting mitophagy through the PINK1/parkin signaling pathway

Splicing-dependent restriction of the HBZ gene by Tax underlies biphasic HTLV-1 infection

Dietary Riboflavin Supplementation Suppresses Colorectal Cancer Progression by Restoring the Function Effector of CD8+ T Cells

PRRX1 drives pericyte–endothelial cell crosstalk in pathological retinal angiogenesis via regulation of the IGFBP7–JAK1–STAT3 axis

Metabolism archetype cancer cells induce protumor TREM2+ macrophages via oxLDL-mediated metabolic interplay in hepatocellular carcinoma

Hydrogen sulfide preserves the function of senescent endothelium through SIRT2 mediated inflammatory inhibition

Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)-stabilized lncRNA small nucleolar RNA host gene 15 (Snhg15) modulates hematopoietic injury induced by γ-ray irradiation via m6A modification

Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p

Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p

"GalNAc-siRNA conjugates mediate the silencing of the parasite-derived lncRNA: A novel therapeutic approach for liver fluke-induced liver fibrosis"

"ProgrammedCellDeathProtein10(PDCD10)Regulates VesicleTraffickingandContributestotheProgressionof ClearCellRenalCellCarcinoma"

Homeobox C6 plays an oncogenic role in bladder cancer

Total ginsenosides and ginsenoside Rb2 delay hepatocyte senescence by regulating NAD+ metabolism and promoting IDO2/QPRT expression

Discovery of Yersinia LcrV as a novel biased agonist of formyl peptide receptor 1 to bi-directionally modulate intracellular kinases in triple-negative breast cancer

The comprehensive transcriptomic atlas of porcine immune tissues and the early peripheral blood mononuclear cell (PBMC) immune dynamics reveal core immune genes

Cancer-Associated Fibroblasts Foster a High-Lactate Microenvironment to Drive Perineural Invasion in Pancreatic Cancer

circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer

The Pb tolerance initiated by LdZIP8 in Lymantria dispar larvae: An effective defense against heavy metal stress

Function of lamp2 Gene Response to Vibrio vulnificus Infection and LPS Stimulation in the Half-Smooth Tongue Sole (Cynoglossus semilaevis)

Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study

Integrative bioinformatics and experimental analyses identify U2SURP as a novel lactylation-related prognostic signature in esophageal carcinoma

Exosomes of human adipose stem cells mitigate irradiation injury to salivary glands by inhibiting epithelial-mesenchymal transition through miR-199a-3p targeting Twist1 and regulating TGFβ1/Smad3 pathway

Cold atmospheric plasma potentiates ferroptosis via EGFR(Y1068)-mediated dual axes on GPX4 among triple negative breast cancer cells

IL-8 promotes pyroptosis through ERK pathway and mediates glucocorticoid resistance in chronic rhinosinusitis with nasal polyps

Circular RNA circPHLPP2 promotes tumor growth and anti-PD-1 resistance through binding ILF3 to regulate IL36γ transcription in colorectal cancer

Microplastics accumulated in breast cancer patients lead to mitophagy via ANXA2-mediated endocytosis and IL-17 signaling pathway

Prebiotic stachyose inhibits PRDX5 activity and castration-resistant prostate cancer development

Fluoride exposure-induced gut microbiota alteration mediates colonic ferroptosis through N6-methyladenosine (m6A) mediated silencing of SLC7A11

Lysosomal dysfunction-derived autophagy impairment of gingival epithelial cells in diabetes-associated periodontitis with altered protein acetylation

Construction of a prognostic model for ovarian cancer based on a comprehensive bioinformatics analysis of cuproptosis-associated long non-coding RNA signatures

Arsenic trioxide suppresses lung adenocarcinoma stem cell stemness by inhibiting m6A modification to promote ferroptosis

The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis

Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts

Prognosis and immunotherapy response prediction based on M2 macrophage-related genes in colon cancer

"Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer"

Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy

PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function

"Assessment of prognostic role of a novel 7-lncRNA signature in HCC patients"

SERPINB5 is a prognostic biomarker and promotes proliferation, metastasis and epithelial-mesenchymal transition (EMT) in lung adenocarcinoma

"lncRNA CYTOR Facilitates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating SOX11 via Sponging miR-6512-3p"

"LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway"

Transcriptomic and Functional Approaches Unveil the Role of tmRNA in Zinc Acetate Mediated Levofloxacin Sensitivity in Helicobacter pylori

N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells

Baicalein Induces Hepatic Stellate Cell Senescence and Attenuates Liver Fibrosis via CEBPZ/p53/HK2-Mediated Glycolysis Inhibition

The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer

RNFT2 promotes malignancy of triple-negative breast cancer and predicts poor outcomes

Tea Polyphenols Mitigate Radiation-Induced Ferroptosis and Intestinal Injury by Targeting the Nrf2/HO-1/GPX4 Signaling Pathway

The Potential Biological Roles and Clinical Significance of Anaphase-Promoting Complex Subunit 1 in Colorectal Cancer

Cancer-associated fibroblasts promote oral squamous cell carcinoma progression by targeting ATP7A via exosome-mediated paracrine miR-148b-3p

UBC9: a novel therapeutic target in papillary thyroid carcinoma

CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis

N6-methyladenosine-modified VGLL1 promotes ovarian cancer metastasis through high-mobility group AT-hook 1/Wnt/β-catenin signaling

ALKBH5 Protects Against Hepatic Ischemia–Reperfusion Injury by Regulating YTHDF1-Mediated YAP Expression

METTL14 inhibits malignant progression of oral squamous cell carcinoma by targeting the autophagy-related gene RB1CC1 in an m6A-IGF2BP2-dependent manner

Circ_0039857: A Key Player in Combating Immune Disorders and Ferroptosis in High-Glucose-induced HK-2 Cells and Diabetic Kidney Disease Mice

Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p

RNFT2 promotes malignancy of triple-negative breast cancer and predicts poor outcomes

Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p

circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer

Hsa-miR-526b-5p Regulates the Sensitivity of Colorectal Cancer to 5-Fluorouracil by Targeting TP53 in Organoid Models

Brain‐Derived Exosomal miR‐9‐5p Induces Ferroptosis in Traumatic Brain Injury‐Induced Acute Lung Injury by Targeting Scd1

Regulation of mRNA and miRNA in the response to Salmonella enterica serovar Enteritidis infection in chicken cecum

"Downregulation of hsa_circRNA_0001400 Helps to Promote Cell Apoptosis Through Disruption of the circRNA_0001400–miR-326 Sponge in Cervical Cancer Cells"

Splicing-dependent restriction of the HBZ gene by Tax underlies biphasic HTLV-1 infection

A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer

Chaihu Guizhi Ganjiang decoction attenuates chronic pancreatitis by suppressing acinar cell ferroptosis via regulating p53/SLC7A11/GPX4 pathway

Apoptotic extracellular vesicles from peripancreatic adipose-derived mesenchymal stem cells ameliorate severe acute pancreatitis through the transcription factor EB-mediated autophagy–lysosomal pathway: an experimental study

Remimazolam attenuates traumatic brain injury-induced acute lung injury by suppressing pulmonary epithelial pyroptosis

The m6A reader protein YTHDF2 facilitates HTLV-1 infectious and mitotic propagation by stabilizing Tax RNA

Tenvermectin B, a novel macrocyclic lactone antibiotic, suppresses glioblastoma progression by targeting RhoJ

ZBTB16 promotes the transcription of glycolytic enzyme PFKFB2 to participate in fibrogenesis in septic lung injury

"Obinutuzumab induces lysosomal destabilization via sphingomyelin-dependent inhibition of TRPML2"

"USP25 attenuates the immunosuppressive tumor microenvironment via the deubiquitination of TAB2 in head and neck squamous cell carcinoma"

Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis

Cellular and molecular mechanisms of seahorse male pregnancy

PRRX1 Orchestrates Pericyte–Myofibroblast Transition in Pathological Retinal Fibrosis

A Soluble Receptor for Advanced Glycation End-Products Attenuates Myocardial Ischemia/Reperfusion Injury via Enhancing Glucose Metabolism

CD81 inhibits the proliferation of acute megakaryoblastic leukemia cells

SOX11-mediated CBLN2 Upregulation Contributes to Neuropathic Pain through NF-κB-Driven Neuroinflammation in Dorsal Root Ganglia of Mice

MIOX Aggravated DEHP-Induced Ferroptosis in Chicken Hepatocytes by Targeting STAT3 Phosphorylation

CREB–KIF1A–CGRP-positive feedback loop drives central sensitization in chronic migraine

Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells

Critical role of LdZIP7 in enhancing cadmium tolerance of Lymantria dispar larvae: Functional identification at both the individual and cellular levels

Acetyl zingerone inhibits chondrocyte pyroptosis and alleviates osteoarthritis progression by promoting mitophagy through the PINK1/parkin signaling pathway

Splicing-dependent restriction of the HBZ gene by Tax underlies biphasic HTLV-1 infection

Dietary Riboflavin Supplementation Suppresses Colorectal Cancer Progression by Restoring the Function Effector of CD8+ T Cells

PRRX1 drives pericyte–endothelial cell crosstalk in pathological retinal angiogenesis via regulation of the IGFBP7–JAK1–STAT3 axis

Metabolism archetype cancer cells induce protumor TREM2+ macrophages via oxLDL-mediated metabolic interplay in hepatocellular carcinoma

Hydrogen sulfide preserves the function of senescent endothelium through SIRT2 mediated inflammatory inhibition

Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)-stabilized lncRNA small nucleolar RNA host gene 15 (Snhg15) modulates hematopoietic injury induced by γ-ray irradiation via m6A modification

Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p

Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p

"GalNAc-siRNA conjugates mediate the silencing of the parasite-derived lncRNA: A novel therapeutic approach for liver fluke-induced liver fibrosis"

"ProgrammedCellDeathProtein10(PDCD10)Regulates VesicleTraffickingandContributestotheProgressionof ClearCellRenalCellCarcinoma"

Homeobox C6 plays an oncogenic role in bladder cancer

Total ginsenosides and ginsenoside Rb2 delay hepatocyte senescence by regulating NAD+ metabolism and promoting IDO2/QPRT expression

Discovery of Yersinia LcrV as a novel biased agonist of formyl peptide receptor 1 to bi-directionally modulate intracellular kinases in triple-negative breast cancer

The comprehensive transcriptomic atlas of porcine immune tissues and the early peripheral blood mononuclear cell (PBMC) immune dynamics reveal core immune genes

Cancer-Associated Fibroblasts Foster a High-Lactate Microenvironment to Drive Perineural Invasion in Pancreatic Cancer

circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer

The Pb tolerance initiated by LdZIP8 in Lymantria dispar larvae: An effective defense against heavy metal stress

Function of lamp2 Gene Response to Vibrio vulnificus Infection and LPS Stimulation in the Half-Smooth Tongue Sole (Cynoglossus semilaevis)

Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study

Integrative bioinformatics and experimental analyses identify U2SURP as a novel lactylation-related prognostic signature in esophageal carcinoma

Exosomes of human adipose stem cells mitigate irradiation injury to salivary glands by inhibiting epithelial-mesenchymal transition through miR-199a-3p targeting Twist1 and regulating TGFβ1/Smad3 pathway

Cold atmospheric plasma potentiates ferroptosis via EGFR(Y1068)-mediated dual axes on GPX4 among triple negative breast cancer cells

IL-8 promotes pyroptosis through ERK pathway and mediates glucocorticoid resistance in chronic rhinosinusitis with nasal polyps

Circular RNA circPHLPP2 promotes tumor growth and anti-PD-1 resistance through binding ILF3 to regulate IL36γ transcription in colorectal cancer

Microplastics accumulated in breast cancer patients lead to mitophagy via ANXA2-mediated endocytosis and IL-17 signaling pathway

Prebiotic stachyose inhibits PRDX5 activity and castration-resistant prostate cancer development

Fluoride exposure-induced gut microbiota alteration mediates colonic ferroptosis through N6-methyladenosine (m6A) mediated silencing of SLC7A11

Lysosomal dysfunction-derived autophagy impairment of gingival epithelial cells in diabetes-associated periodontitis with altered protein acetylation

Construction of a prognostic model for ovarian cancer based on a comprehensive bioinformatics analysis of cuproptosis-associated long non-coding RNA signatures

Arsenic trioxide suppresses lung adenocarcinoma stem cell stemness by inhibiting m6A modification to promote ferroptosis

The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis

Virtual Screening, Molecular Dynamics, and Mechanism Study of Homeodomain-Interacting Protein Kinase 2 Inhibitor in Renal Fibroblasts

Baicalein Induces Hepatic Stellate Cell Senescence and Attenuates Liver Fibrosis via CEBPZ/p53/HK2-Mediated Glycolysis Inhibition

Prognosis and immunotherapy response prediction based on M2 macrophage-related genes in colon cancer

The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer

"Identification of PRDX5 as A Target for The Treatment of Castration-Resistant Prostate Cancer"

RNFT2 promotes malignancy of triple-negative breast cancer and predicts poor outcomes

Tea Polyphenols Mitigate Radiation-Induced Ferroptosis and Intestinal Injury by Targeting the Nrf2/HO-1/GPX4 Signaling Pathway

Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy

Circ_0039857: A Key Player in Combating Immune Disorders and Ferroptosis in High-Glucose-induced HK-2 Cells and Diabetic Kidney Disease Mice

The Potential Biological Roles and Clinical Significance of Anaphase-Promoting Complex Subunit 1 in Colorectal Cancer

PHB2 ameliorates Doxorubicin-induced cardiomyopathy through interaction with NDUFV2 and restoration of mitochondrial complex I function

Hsa_circ_0018909 promotes non-small cell lung cancer by directly regulating hsa-miR-513b-5p

RNFT2 promotes malignancy of triple-negative breast cancer and predicts poor outcomes

Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11-mediated competitive protein degradation and synergizes with miRNA-146b-5p

Cancer-associated fibroblasts promote oral squamous cell carcinoma progression by targeting ATP7A via exosome-mediated paracrine miR-148b-3p

"Assessment of prognostic role of a novel 7-lncRNA signature in HCC patients"

UBC9: a novel therapeutic target in papillary thyroid carcinoma

circ-1584 selectively promotes the antitumor activity of the oncolytic virus M1 on pancreatic cancer

SERPINB5 is a prognostic biomarker and promotes proliferation, metastasis and epithelial-mesenchymal transition (EMT) in lung adenocarcinoma

Hsa-miR-526b-5p Regulates the Sensitivity of Colorectal Cancer to 5-Fluorouracil by Targeting TP53 in Organoid Models

CRISPR-Cas12a2-based rapid and sensitive detection system for target nucleic acid

CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis

"lncRNA CYTOR Facilitates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating SOX11 via Sponging miR-6512-3p"

N6-methyladenosine-modified VGLL1 promotes ovarian cancer metastasis through high-mobility group AT-hook 1/Wnt/β-catenin signaling

Hairpin-locker mediated CRISPR/Cas tandem system for ultrasensitive detection of DNA without pre-amplification

Brain‐Derived Exosomal miR‐9‐5p Induces Ferroptosis in Traumatic Brain Injury‐Induced Acute Lung Injury by Targeting Scd1

"LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway"

ALKBH5 Protects Against Hepatic Ischemia–Reperfusion Injury by Regulating YTHDF1-Mediated YAP Expression

"Icariin promotes osteogenic differentiation through the mmu_circ_0000349/mmu-miR-138-5p/Jumonji domain-containing protein-3 axis"

Regulation of mRNA and miRNA in the response to Salmonella enterica serovar Enteritidis infection in chicken cecum

Transcriptomic and Functional Approaches Unveil the Role of tmRNA in Zinc Acetate Mediated Levofloxacin Sensitivity in Helicobacter pylori

METTL14 inhibits malignant progression of oral squamous cell carcinoma by targeting the autophagy-related gene RB1CC1 in an m6A-IGF2BP2-dependent manner

N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells

Autophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA

"Downregulation of hsa_circRNA_0001400 Helps to Promote Cell Apoptosis Through Disruption of the circRNA_0001400–miR-326 Sponge in Cervical Cancer Cells"

Engineering an ATP-saving mevalonate pathway for high-efficiency S-(+)-linalool production in Serratia marcescens

"Metabolic flux balancing and enhanced expression of engineered Paeonia lactiflora pinene synthase for high-yield α-pinene production in Serratia marcescens HBQA7"

"Highly efficient spermidine production system in Escherichia coli BL21 (DE3) based on precursor metabolic modules optimization and carboxyaminopropylagmatine pathway construction"

Rational Enzyme Modification and Expression Enhancement Strategies for 1,8-cineole Production in Serratia marcescens Cell Factories

Antibiotic-free high-yield (-)-α-bisabolol production in Serratia marcescens via metabolic engineering and genomic integration of mevalonate pathway genes

High-Efficiency Synthesis of β-Caryophyllene in Serratia marcescens via an Aeropyrum-Type MVA Pathway and Enzyme Engineering

Polydatin Attenuates Cognitive Deficits and Neuroinflammation by Inhibiting the P2X7/NLRP1 Inflammasome Pathway in APP/PS1 Mice and Aβ-Treated HT22 Cells

Amplification-free cancer diagnosis based on inhibition of Cas12a activity by site-specific 5mC-modified cfDNA

Engineering Glycosyltransferase by Semi-Rational Design for Highly Regioselective Synthesis of Polydatin

High-Efficiency Production of (S)-Limonene in Monoterpene-Resistant Serratia Marcescens through Bicistronic Translation of Engineered (S)-Limonene Synthase

Boosting (E)-Nerolidol Yield in Serratia marcescens via Nerolidol Synthase Engineering and Competitive Pathway Knockout

GhWRKY41 Confers Salt Tolerance by Enhancing Photosynthetic Capacity in Cotton (Gossypium hirsutum)

TEA domain transcription factor 3 suppresses aortic and left ventricular remodeling via transcriptional activation of PDZ domain containing 1

"CORRELATIONS OF P53, SLC7A11, CD3+ T CELLS, AND CD8+ T CELLS WITH PATHOLOGICAL FEATURES AND PROGNOSIS IN ENDOMETRIAL CARCINOMA: INSIGHTS FROM AN ASIAN COHORT"

Tanshinone IIA suppresses the proliferation and fibrosis of mesangial cell in diabetic nephropathy though WTAP-mediated m6A methylation

Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease

Carboxylesterase 1 regulates peroxisome proliferator-activated receptor gamma to inhibit the growth and metastasis of breast cancer cells

Ziziphi Spinosae semen extract ameliorates insomnia by regulating hypothalamic GABA/Glu balance and gut microbiota Lactobacillus johnsonii

Identification of genetic indicators linked to immunological infiltration in idiopathic pulmonary fibrosis

Regulation of Dendritic Cell Function by RFX5 through Interaction with HDAC2 and Its Mechanism in Pediatric Asthma

Engineering an Extremely Monoterpene-Tolerant Serratia marcescens for High-Yield Geraniol Production via a Rationally Modified Insect Phosphatase

Production of geraniol by a solvent-tolerant Serratia marcescens without the formation of geraniol derivatives

Hybrid Methylotrophic Pathway in Serratia marcescens for Sustainable Terpenoid Biosynthesis

Multi-omics integration reveals the regulatory mechanisms of APC and CREB5 genes in lipid biosynthesis and fatty acid composition in pigs

Semi-rational engineering of glucosamine-6-phosphate deaminase for catalytic synthesis of glucosamine from D-fructose

"Construction of a CRISPR‐Cas9‐Based Genetic Editing Tool for Serratia marcescens Using a Stationary Phase Promoter and Its Application in Putrescine Production"

Rapid detection assays for Bacillus anthracis, Yersinia pestis, and Brucella spp. via triplex-recombinase polymerase amplification

Development of a vitamin B5 hyperproducer in Escherichia coli by multiple metabolic engineering

Ferulic Acid Relieves the Oxidative Stress Induced by Oxidized Fish Oil in Oriental River Prawn (Macrobrachium Nipponense) with the Emphasis on Lipid Metabolism and Gut Microbiota

Characterization and Application of a Stationary Phase Promoter Library from Serratia marcescens

Hairpin-locker mediated CRISPR/Cas tandem system for ultrasensitive detection of DNA without pre-amplification

Synergetic Engineering of Multiple Pathways for De Novo (2S)-Naringenin Biosynthesis in Saccharomyces cerevisiae

Engineering an ATP-saving mevalonate pathway for high-efficiency S-(+)-linalool production in Serratia marcescens

"Metabolic flux balancing and enhanced expression of engineered Paeonia lactiflora pinene synthase for high-yield α-pinene production in Serratia marcescens HBQA7"

"Highly efficient spermidine production system in Escherichia coli BL21 (DE3) based on precursor metabolic modules optimization and carboxyaminopropylagmatine pathway construction"

Rational Enzyme Modification and Expression Enhancement Strategies for 1,8-cineole Production in Serratia marcescens Cell Factories

High-Efficiency Synthesis of β-Caryophyllene in Serratia marcescens via an Aeropyrum-Type MVA Pathway and Enzyme Engineering

Engineering Glycosyltransferase by Semi-Rational Design for Highly Regioselective Synthesis of Polydatin

High-Efficiency Production of (S)-Limonene in Monoterpene-Resistant Serratia Marcescens through Bicistronic Translation of Engineered (S)-Limonene Synthase

Promoter demethylation of cerebellin 2 by ten-eleven translocation 3 contributes to peripheral sensitization in trigeminal neuropathic pain of mice

Itaconic acid production from corn stover hydrolysates for a newly isolated Aspergillus terreus through adaptive evolution

De novo production of LNnT by metabolic engineering of Saccharomyces cerevisiae as cell factory

Taurine-mediated gene transcription and cell membrane permeability reinforced co-production of bioethanol and Monascus azaphilone pigments for a newly isolated Monascus purpureus

Isolation and genomic characterization of chicken infectious anemia virus in Jiangsu province of China during 2020–2022

Development of Terminator–Promoter Bifunctional Elements for Application in Saccharomyces cerevisiae Pathway Engineering

"Characterisation of Aldo-keto Reductases From Lactobacillus reuteri DSM20016"

"Heterologous expression and characterization of a borneol dehydrogenase from Arabidopsis lyrate and its application for the enzymatic resolution of rac-camphor"

"Glycosylation Modification Enhances (2S)‑Naringenin Production in Saccharomyces cerevisiae"

"Enhancing Squalene Production in Saccharomyces cerevisiae by Metabolic Engineering and Random Mutagenesis"

Expression and characterization of a raw-starch glucoamylase from Aspergillus fumigatus

MIOX Aggravated DEHP-Induced Ferroptosis in Chicken Hepatocytes by Targeting STAT3 Phosphorylation

CREB–KIF1A–CGRP-positive feedback loop drives central sensitization in chronic migraine

Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells

Hydrogen sulfide preserves the function of senescent endothelium through SIRT2 mediated inflammatory inhibition

Berberine attenuates obesity-induced skeletal muscle atrophy via regulation of FUNDC1 in skeletal muscle of mice

Single-cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia–reperfusion injury

PAI-1 Derived from Alveolar Type 2 Cells Drives Aging-Associated Pulmonary Fibrosis

A Novel Four-CpG Prognostic Risk Score Model Predicts Survival and Guides Therapy in Patients with Head and Neck Squamous Cell Carcinoma

"The Novel circRNA_0022587/miR-216a-5p/PRKCE Axis Restricts Glioblastoma (GBM) Progression"

Enhanced meningeal lymphatic drainage alleviates cognitive dysfunction induced by anesthesia and surgery in aged mice

MIR4726EccDNA drives bortezomib resistance in multiple myeloma by enhancing MIR4726-5p/NXF1/NKIRAS2 axis dependent autophagy